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Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates.

Kristina Schaefer,M. Peifer

2019 · DOI: 10.1016/j.devcel.2019.01.025
Developmental Cell · 176 Citations

TLDR

New insights into destruction complex activity and regulation are discussed, highlighting parallels to the control of other cell biological processes by biomolecular condensates that form by phase separation to suggest that the destruction complex acts as a biomolecules condensate in Wnt pathway regulation.