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Viscoelastic Gel-Strip Model for the Simulation of Migrating Cells

Y. Sakamoto,S. Prudhomme,M. Zaman

2011 · DOI: 10.1007/s10439-011-0360-z
Annals of Biomedical Engineering · 25 Citations

TLDR

An axisymmetric viscoelastic gel-strip model of a single cell to investigate a cell migrating in native-like environments indicates that amoeboid migration is more suited for low-resistance environment while mesenchymal migration is preferred in high-Resistance environment, which would explain the versatile behaviors of tumor cells in complex environments.