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Vedolizumab as induction and maintenance therapy for Crohn's disease.

W. Sandborn,B. Feagan,14 Authors,A. Parikh

2013 · DOI: 10.1056/NEJMoa1215739
New England Journal of Medicine · 2,068 Citations

TLDR

Vedolizumab-treated patients with active Crohn's disease were more likely than patients receiving placebo to have a remission, but not a CDAI-100 response, at week 6; patients with a response to induction therapy who continued to receive vedolIZumab (rather than switching to placebo) were morelikely to be in remission at week 52.