Vaginal absorption of a potent luteinizing hormone-releasing hormone analogue (leuprolide) in rats II: mechanism of absorption enhancement with organic acids.
Vaginal absorption of a potent luteinizing hormone-releasing hormone analogue (leuprolide) in rats II: mechanism of absorption enhancement with organic acids.
H. Okada,I. Yamazaki,T. Yashiki,H. Mima
1983 · DOI: 10.1002/JPS.2600720118
Journal of Pharmacy and Science · 63 Citations
TLDR
The results suggest that the acidifying and chelating abilities of the acids may result in a potent enhancement of the vaginal absorption of leuprolide.