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Utility of Drosophila for studying hypoxia-inducible factor (HIF) in neurodegenerative diseases: Advantages versus limitations.

Z. Serebrovska,Lei Xi,4 Authors,Oksana Maksymchuk

2025 · DOI: 10.1016/j.brainres.2025.149953
Brain Research · 0 Citations

TLDR

The role of HIF-1α/Sima in modulating neuroprotective pathways, including its interactions with DJ-1, SNCA, SNCA (Alpha-synuclein), and the mTOR-autophagy axis are discussed.