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UPARSE: highly accurate OTU sequences from microbial amplicon reads

Robert C. Edgar

2013 · DOI: 10.1038/nmeth.2604
Nature Methods · 14,689 Citations

TLDR

The UPARSE pipeline reports operational taxonomic unit (OTU) sequences with ≤1% incorrect bases in artificial microbial community tests, compared with >3% correct bases commonly reported by other methods.