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Unveiling the Scientific Landscape and Trends of Cutaneous Immune-Related Adverse Events: A Bibliometric Analysis

Danli Zhong,Chengyu Shi

2026 · DOI: 10.7759/cureus.105013
Cureus · 0 Citations

TLDR

Bibliometric analysis reveals that research on cirAEs has grown steadily, with enhanced global collaboration, and reflects a deeper investigation into underlying mechanisms and a heightened emphasis on personalized treatment approaches, thus offering insights for future interdisciplinary research aimed at optimizing clinical management and improving treatment safety.

Abstract

With the widespread use of immune checkpoint inhibitors (ICIs) in cancer treatment, cutaneous immune-related adverse events (cirAEs) have attracted increasing attention. This bibliometric analysis reveals that research on cirAEs has grown steadily, with enhanced global collaboration. The focus has progressively shifted from early studies on specific agents and conditions toward severe cutaneous adverse reactions, diverse cancer types, and systemic clinical management strategies. This evolution reflects a deeper investigation into underlying mechanisms and a heightened emphasis on personalized treatment approaches, thus offering insights for future interdisciplinary research aimed at optimizing clinical management and improving treatment safety.