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Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

Yukitaka Ito,Sou Nakamura,25 Authors,K. Eto

2018 · DOI: 10.1016/j.cell.2018.06.011
Cell · 231 Citations

TLDR

This study provides a concept in which a coordinated physico-chemical mechanism promotes platelet biogenesis and an innovative strategy for ex vivo platelet manufacturing is provided.