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Tungsten enzymes play a role in detoxifying food and antimicrobial aldehydes in the human gut microbiome

G. Schut,M. Thorgersen,3 Authors,M. Adams

2021 · DOI: 10.1073/pnas.2109008118
Proceedings of the National Academy of Sciences of the United States of America · 30 Citations

TLDR

It is demonstrated that two model gut microbes assimilate tungsten into multiple WOR enzymes and that some of these enzymes catalyze the conversion of gut aldehydes to the corresponding acid, likely as a detoxification strategy to remove these reactive compounds.