Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
M. Plattén,E. Nollen,2 Authors,C. Opitz
2019 · DOI: 10.1038/s41573-019-0016-5
Nature reviews. Drug discovery · 1,143 Citations
TLDR
An overview of the physiological and pathophysiological roles of tryptophan metabolism is provided, focusing on the clinical potential and challenges associated with targeting this pathway.