Transposable Element Derepression-mediated IFN-I Signaling Enhances Stem/Progenitor Cell Activity After Irradiation
Transposable Element Derepression-mediated IFN-I Signaling Enhances Stem/Progenitor Cell Activity After Irradiation
D. Cinat,Ryan van der Wal,7 Authors,R. Coppes
2025 · DOI: 10.1101/2024.02.14.580306
bioRxiv · 3 Citations
TLDR
A pro-regenerative role of TE derepression-mediated IFN-I response is revealed suggesting this pathway as a promising therapeutic target to mitigate radiation-induced side effects.