Toxicology, mode of action and target site-mediated resistance to insecticides acting on chloride channels.
Toxicology, mode of action and target site-mediated resistance to insecticides acting on chloride channels.
J. Bloomquist
1993 · DOI: 10.1016/0742-8413(93)90138-B
106 Citations
TLDR
The results of biochemical and neurophysiological studies indicate that the gamma-aminobutyric acid-gated chloride channel is an important, if not the primary site of action for these compounds, and new compounds with a similar mode of action must be used judiciously in order to suppress or delay the re-emergence of widespread resistance.