The retinal choroid as an oculovascular biomarker for Alzheimer's dementia: A histopathological study in severe disease
The retinal choroid as an oculovascular biomarker for Alzheimer's dementia: A histopathological study in severe disease
S. Asanad,F. Ross-Cisneros,4 Authors,A. Sadun
2019 · DOI: 10.1016/j.dadm.2019.08.005
Alzheimer's & Dementia · 41 Citations
TLDR
This work pursued a histopathological approach to assess choroidal thickness and vascular morphology in severe disease and proposed the retinal choroid as a potential oculovascular biomarker for Alzheimer's disease.
Abstract
Previous in vivo optical coherence tomography studies have proposed the retinal choroid as a potential oculovascular biomarker for Alzheimer's disease (AD). However, the clinical use of the choroid as a purported surrogate marker remains poorly understood. We pursued a histopathological approach to assess choroidal thickness and vascular morphology in severe disease.