The reliability of diagnostic techniques in the diagnosis and management of malaria in the absence of a gold standard.
The reliability of diagnostic techniques in the diagnosis and management of malaria in the absence of a gold standard.
L. Ochola,P. Vounatsou,3 Authors,Charles R. Newton
2006 · DOI: 10.1016/S1473-3099(06)70579-5
Lancet. Infectious Diseases (Print) · 229 Citations
TLDR
Overall, histidine-rich protein 2 (HRP2)-based dipsticks showed a high sensitivity and specificity for Plasmodium falciparum in endemic areas and epidemiological studies, and HRP2 dipsticks and acridine orange could provide an alternative in the absence of a gold standard.