The relationship between tirasemtiv serum concentration and functional outcomes in patients with ALS
The relationship between tirasemtiv serum concentration and functional outcomes in patients with ALS
J. Shefner,A. Wolff,L. Meng
2013 · DOI: 10.3109/21678421.2013.817587
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · 15 Citations
TLDR
Tirasemtiv appears to have concentration-dependent beneficial effects on both function and measures of strength and endurance when administered for up to 21 days, even when time is eliminated as a cofactor.