The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids
The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids
P. Puri,Kalyani Daita,14 Authors,A. Sanyal
2018 · DOI: 10.1002/hep.29359
Hepatology · 324 Citations
TLDR
NAFLD is associated with significantly altered circulating BA composition, likely unaffected by type 2 diabetes, and correlated with histological features of NASh; these observations provide the foundation for future hypothesis‐driven studies of specific effects of BAs on specific aspects of NASH.