The Collagen-Binding Protein Cnm Is Required for Streptococcus mutans Adherence to and Intracellular Invasion of Human Coronary Artery Endothelial Cells
The Collagen-Binding Protein Cnm Is Required for Streptococcus mutans Adherence to and Intracellular Invasion of Human Coronary Artery Endothelial Cells
J. Abranches,J. H. Miller,3 Authors,J. Lemos
2011 · DOI: 10.1128/IAI.00767-10
Infection and Immunity · 167 Citations
TLDR
It is demonstrated that in addition to OMZ175 and B14, three other strains (NCTC11060, LM7, and OM50E) of the less prevalent serotypes e and f are able to invade primary human coronary artery endothelial cells (HCAEC) and represents an important virulence factor of S. mutans that may contribute to cardiovascular infections and pathologies.