The classification of skin irritants by human patch test.
The classification of skin irritants by human patch test.
D. Basketter,M. Chamberlain,3 Authors,M. York
1997 · DOI: 10.1016/S0278-6915(97)00053-7
Food and Chemical Toxicology · 107 Citations
TLDR
The background to the development of the human 4 hour patch test is provided, the value of the method in providing 'gold standard' data for the identification of those substances (or preparations) which should be classified as irritant to skin in European legislation is discussed and recommendations are made.