Tackling soil diversity with the assembly of large, complex metagenomes
Tackling soil diversity with the assembly of large, complex metagenomes
R. Willette,J. Lepore,12 Authors,J. Yates
2014 · DOI: 10.1073/pnas.1402564111
Proceedings of the National Academy of Sciences of the United States of America · 308 Citations
TLDR
This work combines two preassembly filtering approaches—digital normalization and partitioning—to generate previously intractable large metagenome assemblies, which result in assemblies nearly identical to assemblies from unprocessed data.
