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Tackling soil diversity with the assembly of large, complex metagenomes

R. Willette,J. Lepore,12 Authors,J. Yates

2014 · DOI: 10.1073/pnas.1402564111
Proceedings of the National Academy of Sciences of the United States of America · 308 Citations

TLDR

This work combines two preassembly filtering approaches—digital normalization and partitioning—to generate previously intractable large metagenome assemblies, which result in assemblies nearly identical to assemblies from unprocessed data.