SUPPRESSION OF GLYCOLYSIS IN RAT BRAIN IN VIVO CHLORPROMAZINE, RESERPINE, AND PHENOBARBITAL.
SUPPRESSION OF GLYCOLYSIS IN RAT BRAIN IN VIVO CHLORPROMAZINE, RESERPINE, AND PHENOBARBITAL.
K. Gey,M. Rutishauser,A. Pletscher
1965 · DOI: 10.1016/0006-2952(65)90223-6
Biochemical Pharmacology · 35 Citations
TLDR
The finding of decreased hexose phosphates in the brain supports the hypothesis that central depressant drugs suppress glycolysis in the central nervous system in vivo possibly by a diminution of glucose phosphorylation.