Striatal metabolic rate and clinical response to neuroleptics in schizophrenia.
Striatal metabolic rate and clinical response to neuroleptics in schizophrenia.
M. Buchsbaum,S. Potkin,10 Authors,W. Bunney
1992 · DOI: 10.1001/ARCHPSYC.1992.01820120054008
Archives of General Psychiatry · 178 Citations
TLDR
A low metabolic rate in the caudate nucleus and putamen in schizophrenic patients while they were not receiving medication was found to predict a favorable clinical response to haloperidol, and this is the first such trial with positron emission tomography to be reported.