Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA.
Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA.
T. Mukhopadhyay,M. Tainsky,Adriana C. Cavender,J. Roth
1991 · DOI: 10.1016/0169-5002(91)90412-y
Cancer Research · 205 Citations
TLDR
The growth of H460a tumors in nu/nu mice was substantially reduced by expressed K-ras antisense RNA, whereas expression of H-ras and N-ras was unchanged.