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Single-cell RNA sequencing to explore immune cell heterogeneity

Efthymia Papalexi,R. Satija

2017 · DOI: 10.1038/nri.2017.76
Nature reviews. Immunology · 1,345 Citations

TLDR

How scRNA-seq can be used to deconvolve immune system heterogeneity by identifying novel distinct immune cell subsets in health and disease, characterizing stochastic heterogeneity within a cell population and building developmental 'trajectories' for immune cells is discussed.