Sequence heterogeneity of cannabidiolic- and tetrahydrocannabinolic acid-synthase in Cannabis sativa L. and its relationship with chemical phenotype.
Sequence heterogeneity of cannabidiolic- and tetrahydrocannabinolic acid-synthase in Cannabis sativa L. and its relationship with chemical phenotype.
C. Onofri,E. D. de Meijer,G. Mandolino
2015 · DOI: 10.1016/j.phytochem.2015.03.006
Phytochemistry · 121 Citations
TLDR
CBDAS is considered as the ancestral type of THCA- and CBDA-synthases because the amount of variation was found to be higher within the CBDAS sequence family than in the THCAS family, suggesting a more recent evolution of TH CA-forming enzymes from the CBDAs group.