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Semaglutide reduces vascular inflammation investigated by PET in a rabbit model of advanced atherosclerosis

Jacob K. Jensen,T. Binderup,3 Authors,A. Kjaer

2022 · DOI: 10.1016/j.atherosclerosis.2022.03.032
Atherosclerosis · 29 Citations

TLDR

Semaglutide decreased vascular uptake of tracers imaging activated macrophages and cellular metabolism but not micro-calcifications compared to a saline placebo supports the hypothesis that semaglUTide reduces atherosclerotic inflammation by means of decreased activated Macrophage activity.