Requirements for Transitional Endoplasmic Reticulum Site Structure and Function in Saccharomyces cerevisiae
Requirements for Transitional Endoplasmic Reticulum Site Structure and Function in Saccharomyces cerevisiae
Polina Shindiapina,C. Barlowe
2010 · DOI: 10.1091/mbc.E09-07-0605
Molecular Biology of the Cell · 60 Citations
TLDR
This study characterizes tER sites in Saccharomyces cerevisiae and probes protein and lipid requirements for tER site structure and function.
Abstract
Secretory proteins are exported from the ER at specialized regions known as transitional ER (tER). COPII proteins are enriched at tER sites, but mechanisms underlying assembly and maintenance are unclear. This study characterizes tER sites in Saccharomyces cerevisiae and probes protein and lipid requirements for tER site structure and function.