Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
A. Franke,Tobias Balschun,8 Authors,S. Schreiber
2008 · DOI: 10.1038/ng.148
Nature Genetics · 391 Citations
TLDR
Investigating previously reported susceptibility loci in a German sample of individuals with Crohn's disease or ulcerative colitis and healthy controls identified variants in 3p21.31, NKX2-3 and CCNY as susceptibility factors for both diseases, whereas variants in PTPN2, HERC2 and STAT3 were associated only with ulcers.