Regulatory T cells: mechanisms of differentiation and function.
Regulatory T cells: mechanisms of differentiation and function.
Steven Z. Josefowicz,Li-Fan Lu,A. Rudensky
2012 · DOI: 10.1146/annurev.immunol.25.022106.141623
Annual Review of Immunology · 2,769 Citations
TLDR
Cellular and molecular mechanisms in the differentiation and function of regulatory T cells and their role in autoimmune and autoinflammatory disorders, allergy, acute and chronic infections, cancer, and metabolic inflammation are discussed.