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Regulation of mitochondrial biogenesis through TFAM-mitochondrial DNA interactions: Useful insights from aging and calorie restriction studies.

A. Picca,A. Lezza

2015 · DOI: 10.1016/j.mito.2015.10.001
Mitochondrion (Amsterdam. Print) · 249 Citations

TLDR

The tissue-specific regulation of mitochondrial biogenesis in aging and calorie restriction (CR) highlights the relevance of modulation of TFAM-mtDNA interactions.