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Reduced EEG Responses to Standard and Target Auditory Stimuli in Bipolar Disorder and the Impact of Psychotic Features: Analysis of ERPs, Spectral Power, and Inter-Trial Coherence

N. Lundin,Lisa A. Bartolomeo,B. O’Donnell,W. Hetrick

2017 · DOI: 10.1111/bdi.12561
Bipolar Disorders · 14 Citations

TLDR

Examination of early and late ERPs in temporal and frequency domains in a bipolar sample with and without current psychotic features found reductions in P3b event‐related potential response.

Abstract

Bipolar disorder (BD) is associated with reductions in the P3b event‐related potential (ERP) response to target auditory stimuli, which suggests deficits in context updating. Previous studies have typically examined these responses in the temporal domain, which may not capture alterations in specific frequencies of phase‐locked or induced electrophysiological activity. Therefore, the present study examined early and late ERPs in temporal and frequency domains in a bipolar sample with and without current psychotic features.