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Randomized Controlled Trial of Inhaled Nitric Oxide for the Treatment of Microcirculatory Dysfunction in Patients With Sepsis*

S. Trzeciak,L. Glaspey,7 Authors,S. Hollenberg

2014 · DOI: 10.1097/CCM.0000000000000549
Critical Care Medicine · 54 Citations

TLDR

Following macrocirculatory optimization, inhaled nitric oxide at 40 ppm did not augment microcirculatory perfusion in patients with sepsis and improved microcirculation would improve lactate clearance and multiple organ dysfunction.