Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
Manja Barthel,S. Hapfelmeier,6 Authors,W. Hardt
2003 · DOI: 10.1128/IAI.71.5.2839-2858.2003
Infection and Immunity · 1,035 Citations
TLDR
The results demonstrate that streptomycin-pretreated mice offer a unique infection model that allows for the first time to use mutants of both the pathogen and the host to study the molecular mechanisms of enteric salmonellosis.