Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets.
Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets.
J. Semple,Rukhsana Aslam,2 Authors,J. Freedman
2007 · DOI: 10.1182/BLOOD-2006-12-062695
Blood · 151 Citations
TLDR
The results suggest that, in the presence of antiplatelet antibodies, bacterial products can significantly alter platelet phagocytosis, and this may have relevance to how Gram-negative infections enhance platelet destruction in some patients with AITP.
