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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

Michael Karin,Y. Ben-Neriah

2000 · DOI: 10.1146/ANNUREV.IMMUNOL.18.1.621
Annual Review of Immunology · 4,967 Citations

TLDR

Recent progress has been made in understanding the details of the signaling pathways that regulate NF-kappaB activity, particularly those responding to the proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1.