Peroxisome proliferator-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis.
Peroxisome proliferator-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis.
Andrew C. Li,W. Palinski
2006 · DOI: 10.1146/ANNUREV.PHARMTOX.46.120604.141247
Annual Review of Pharmacology and Toxicology · 85 Citations
TLDR
With the development of drugs selectively activating PPARs, a new arsenal of drugs specifically targeting to the macrophage/foam cell may potentially have a profound impact on how the authors treat cardiovascular disease.