Outer Membrane Vesicles (OMVs) Produced by Gram-Negative Bacteria: Structure, Functions, Biogenesis, and Vaccine Application
Outer Membrane Vesicles (OMVs) Produced by Gram-Negative Bacteria: Structure, Functions, Biogenesis, and Vaccine Application
Noemi Furuyama,M. Sircili
2021 · DOI: 10.1155/2021/1490732
BioMed Research International · 122 Citations
TLDR
This work has shown that Gram-negative bacteria produce outer membrane vesicles with 10 to 300 nm of diameter, and their capacity to be combined with antigens impact in the future to the development of vaccines.
Abstract
Gram-negative bacteria produce outer membrane vesicles (OMVs) with 10 to 300 nm of diameter. The contribution of OMVs to bacterial pathogenesis is a topic of great interest, and their capacity to be combined with antigens impact in the future to the development of vaccines.