Original Article Highlights From This Issue

Intranasal corticosteroid (INCS) therapy is associated with a lower risk for coronavirus disease 2019 (COVID-19)-related hospitalization, admission to the intensive care unit, and in-hospital mortality. Routine interventions and treatment for asthma patients infected with severe acute respiratory syndrome coronavirus 2 should be continued.Lower Use of Biologics for the Treatment of Asthma in Publicly Insured Individuals Akenroye et al 3969 What is already known about this topic? In a retrospective cohort of adults with asthma and diabetes derived from an electronic health record, metformin use was associated with a lower risk of asthma-related emergency department visits and hospitalizations in a manner that was independent of glycemic control and obesity. Implementing one-bag desensitization protocols may allow simplifying preparation in the pharmacy, reducing the workload for nurses (no bag change, fewer steps), decreasing the risk of errors, and shortening the duration of the procedure, without hampering efficacy or safety.Establishing Amoxicillin Allergy in Children Through Direct Graded Oral Challenge (GOC): Evaluating Risk Factors for Positive Challenges, Safety, and Risk of Cross-Reactivity to Cephalosporines Exius et al 4060 What is already known about this topic?