Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study
Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study
Takahiro Tokunaga,M. Sakashita,38 Authors,S. Fujieda
TLDR
This study wanted to set objective clinical criteria for the diagnosis of refractory CRS, and found that CRSwNP displays more intense eosinophilic infiltration and the presence of Th2 cytokines.
Abstract
Chronic rhinosinusitis (CRS) can be classified into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). CRSwNP displays more intense eosinophilic infiltration and the presence of Th2 cytokines. Mucosal eosinophilia is associated with more severe symptoms and often requires multiple surgeries because of recurrence; however, even in eosinophilic CRS (ECRS), clinical course is variable. In this study, we wanted to set objective clinical criteria for the diagnosis of refractory CRS.