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Novae: a graph-based foundation model for spatial transcriptomics data

Quentin Blampey,Hakim Benkirane,5 Authors,P. Cournède

2025 · DOI: 10.1038/s41592-025-02899-6
Nature Methods · 18 Citations

TLDR

Novae, a self-supervised graph attention network, is a foundation model excelling at a diverse spectrum of spatial transcriptomics modeling and analysis tasks, which supports various downstream tasks, including spatially variable gene or pathway analysis and spatial domain trajectory analysis.