NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on an MRD-based protocol
NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on an MRD-based protocol
M. Svatoň,Aneta Skotnicova,11 Authors,E. Froňková
2022 · DOI: 10.1182/blood.2022017003
Blood · 36 Citations
Abstract
Key Points • NGS MRD evaluation in B-cell precursor acute lymphoblastic leukemia is highly concordant with qPCR while being providing more specific results.• Frontline NGS MRD evaluation is a viable alternative to qPCR assays in future MRD-based acute lymphoblastic leukemia treatment protocols.