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Neopepsee: accurate genome-level prediction of neoantigens by harnessing sequence and amino acid immunogenicity information

Sangwoo Kim,Han Sang Kim,3 Authors,Soonmyung Paik

2018 · DOI: 10.1093/annonc/mdy022
Annals of Oncology · 148 Citations

TLDR

Neopepsee can detect neoantigen candidates with less false positives and be used to determine the prognosis of the patient, and this work found sequence similarity in proteins to known pathogenic epitopes to be a novel feature in classification.