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Multi-feature enhanced protein language models for accurate protein-RNA binding residue prediction

Zhen Feng,Hui Yu,3 Authors,Xiaobo Zhou

2025 · DOI: 10.1007/s40747-025-02065-7
0 Citations

TLDR

MFEPre is presented, a novel multi-feature fusion framework that synergistically combines sequence-based PLMs embeddings, graph-based structural representations, and conventional handcrafted features to enhance the prediction of protein-RNA binding residues.