Monitoring of Blood Vessels and Tissues by a Population of Monocytes with Patrolling Behavior
Monitoring of Blood Vessels and Tissues by a Population of Monocytes with Patrolling Behavior
C. Auffray,D. Fogg,7 Authors,F. Geissmann
2007 · DOI: 10.1126/SCIENCE.1142883
Science · 2,007 Citations
TLDR
It is shown, by direct examination of blood monocyte functions in vivo, that a subset of monocytes patrols healthy tissues through long-range crawling on the resting endothelium, which initiated an early immune response and differentiated into macrophages.