MondoA-Mlx Heterodimers Are Candidate Sensors of Cellular Energy Status: Mitochondrial Localization and Direct Regulation of Glycolysis
MondoA-Mlx Heterodimers Are Candidate Sensors of Cellular Energy Status: Mitochondrial Localization and Direct Regulation of Glycolysis
Christopher L Sans,D. J. Satterwhite,2 Authors,D. Ayer
2006 · DOI: 10.1128/MCB.00657-05
Molecular and Cellular Biology · 121 Citations
TLDR
It is proposed that MondoA communicates information about the intracellular energy state between the mitochondria and the nucleus, resulting in transcriptional activation of glycolytic target genes.