Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses.
Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses.
Francesc Baixauli,R. Acín-Pérez,10 Authors,M. Mittelbrunn
2015 · DOI: 10.1016/j.cmet.2015.07.020
Cell Metabolism · 286 Citations
TLDR
A mechanism by which mitochondria regulate lysosome function to preserve T cell differentiation and effector functions is uncovered, and strategies for intervention in mitochondrial-related diseases are identified.