Methods for Adjusting for Bias Due to Crossover in Oncology Trials
Methods for Adjusting for Bias Due to Crossover in Oncology Trials
K. Ishak,I. Proskorovsky,3 Authors,J. Valle
2014 · DOI: 10.1007/s40273-014-0145-y
PharmacoEconomics (Auckland) · 54 Citations
TLDR
An overview of the crossover problem is provided and circumstances under which it is likely to cause bias are highlighted and how RPSFT and IPCW methods adjust for the bias are described, highlighting the assumptions invoked in the process.