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Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directions.

Huatao Zhou,Zilong Zheng,Chengming Fan,Zijing Zhou

2025 · DOI: 10.1016/j.semcancer.2025.01.001
Seminars in Cancer Biology · 8 Citations

TLDR

The review highlights emerging technologies, such as single-cell sequencing and CRISPR-Cas9, which offer new insights into immunosenescence and its potential as a therapeutic target and outlines future research directions, including strategies for rejuvenating the aging immune system and optimizing immunotherapy for older NSCLC patients.