Mechanism of action of benzodiazepines on GABAA receptors
Mechanism of action of benzodiazepines on GABAA receptors
Claudia Campo‐Soria,Yongchang Chang,D. S. Weiss
2006 · DOI: 10.1038/sj.bjp.0706796
British Journal of Pharmacology · 211 Citations
TLDR
A mechanism in which DZP increases the apparent affinity of the receptor, not by altering the affinity of a closed state, but rather by shifting the equilibrium towards the high‐affinity open state is supported.