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Mechanical modes of 'amoeboid' cell migration.

T. Lämmermann,M. Sixt

2009 · DOI: 10.1016/j.ceb.2009.05.003
Current Opinion in Cell Biology · 662 Citations

TLDR

It is argued that shifting the balance between actin protrusion, actomyosin contraction, and adhesion to the extracellular substrate can explain the different modes of amoeboid movement and that blebbing and gliding are barely extreme variants of one common migration strategy.