Measuring ER stress and the unfolded protein response using mammalian tissue culture system.
Measuring ER stress and the unfolded protein response using mammalian tissue culture system.
C. M. Oslowski,F. Urano
2011 · DOI: 10.1016/B978-0-12-385114-7.00004-0
Methods in Enzymology · 856 Citations
TLDR
The current methods to measure ER stress levels, UPR activation, and subsequent pathways in mammalian cells will assist in understanding the UPR and its contribution to ER stress-related disorders such as diabetes and neurodegeneration.